Ischemic stroke as a consequence of coagulopathy in coronavirus disease

Objective: to compare the state of coagulation system in patients with ischemic stroke and coronavirus disease those without disease. Materials methods. We examined 40 acute period cerebral stroke, aged from 69 87 years (average age 77.30 ± 2.08 years). They were divided into two groups: group I — SARS-CoV-2-positive, II SARS-CoV-2-negative. Group consisted 20 individuals (9 women 11 men) 84 76.9 3.0 included (10 10 72 78.5 2.5 Results. Twelve (60 %) had a moderate severity, 8 (40 severe. The severity neurologic deficits on National Institutes Health Stroke Scale did not differ significantly both clinical it was 14.0 0.7 points, 10.00 1.37 which corresponded significance level p = 0.05. In neurological status, motor sensory observed groups combination speech disorders ataxia. average prothrombin index 101 6 %, 83 2 0.01. fibrinogen 401.0 18.6 mg/dl, 250 12 can lead temporary hypercoagulation development thromboembolism (p < 0.05). I, D-dimer 465 ng/ml, 175 4 ng/ml Conclusions. data suggest that SARS-CoV-2-posi-tive compared SARS-CoV-2-ne-gative ones are characterized by presence coagulopathy, as evidenced higher levels fibrinogen, index, thrombocytopenia, well C-reactive protein indicates an inflammatory process, also causes thrombosis.